Publications
C. Tan, F. Reza, and L. You. Noise-limited frequency signal transmission in gene circuits. Biophysical J. Published online (2007)
C. Tan, H. Song, J. Niemi, and L. You. A synthetic biology challenge: making cells compute. Molecular BioSystems. 3:343 (2007).
P. Marguet, F. Balagadde, C. Tan, and L. You. Biology by design: reduction and synthesis of cellular components and behavior. J. Royal Society Interface. 4:607(2007)
H. Song and L. You. Evolving Sensitivity (Point of View). ACS Chemical Biology. In press (2006).
D. Tu, J. Lee, T. Ozdere, T. Lee, and L. You. Engineering gene circuits: foundations and applications. In Nanotechnology in Biology and Medicine Methods, Devices and Applications, Ed. T. Vo-Dinh. CRC Press. In press (2006)
T. Lee, C. M. Tan, D. Tu, and L. You. Modeling cellular networks. In Bioinformatics: An Engineering Case-Based Approach, Eds. G. Alterovitz & M. Ramoni. In press (2006).
L. You and J. Yin. (2006). Evolutionary design on a budget: robustness and optimality of bacteriophage T7. IEE. Systems Biology. 153:46-52.
F. K. Balagadde *, L. You*, C. Hansen, F. H. Arnold and S. Quake. (2005). Long-term monitoring of bacteria undergoing programmed population control in a microchemostat, Science. 309: 137-140 (* contributed equally).
L. You, R. S. Cox III, R. Weiss, and F. H. Arnold. (2004). Programmed population control by cell-cell communication and regulated killing. Nature. 428: 868-871. Featured in ScienceNow (405:3).
L. You, (2004) Towards computational systems biology. Cell Biochemistry and Biophysics. 40: 167-184
L. You, A. Hoonlor, and J. Yin. (2003) Modeling biological systems using Dynetica – a simulator of dynamic networks. Bioinformatics. 19: 435-436.
R. Srivastava, L. You, J. Summers, and J. Yin. (2002) Stochastic versus deterministic modeling of intracellular viral kinetics. J. Theor. Biol. 218: 309-321.
L. You and J. Yin (2002). Dependence
of epistasis on environment and mutation severity as revealed
by in silico mutagenesis of phage T7. Genetics. 160: 1273-1281
L. You, P. F. Suthers, and J. Yin (2002). Effects of E. coli physiology on growth of phage T7 in vivo and in silico. J. Bacteriology. 184: 1888-1894. (Highlighted in Editors’ Choice of Science (2002), 296: 219)
L. You and J. Yin (2001). Simulating
the growth of viruses. Proceedings of the Pacific
Symposium on Biocomputing: 532-543.
L. You and J. Yin (2000). Patterns
of regulation from mRNA and protein time-series Metabolic
Engineering. 2: 210-217.
D. Endy, L. You, J. Yin, and
L. You and J. Yin (1999). Amplification
and spread of viruses in a growing plaque. J. Theor.
Biol. 200(4): 365-373.
L. You, Q. Liu, Y. Shi, C. X. Wang, M. Lahaye, and V. Tran (1997). The conformational study of b-D-GlcA-(1,4)-L-Rha in solution by NMR and molecular dynamics simulations. Chemical Physics. 224: 81-94.
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